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My Longevity Experiment
January 01, 2025

Best Supplement to Treat Cognitive Decline: Exploring Creatine’s Potential Benefits

Creatine is widely recognized for its role in enhancing muscle performance, but emerging research highlights its potential benefits for brain health and cognitive function. This article delves into the scientific evidence surrounding creatine's impact on neurological health, cognitive decline, and overall brain function.

Creatine and Parkinson’s Disease
Parkinson’s disease is characterized by a severe reduction in dopamine levels, a critical neurotransmitter in the brain. This loss leads to brain cell death and debilitating symptoms such as tremors, muscle function decline, and speech impairments. Studies on mice with Parkinson’s have shown that creatine supplementation can prevent up to 90% of the usual drop in dopamine levels. However, these findings have yet to be replicated in human studies.

For individuals with Parkinson’s, weight training is often recommended to combat muscle function loss. Research has demonstrated that combining creatine supplementation with weight training provides greater improvements in strength and daily functionality than training alone. Nonetheless, a review of five controlled studies involving individuals with Parkinson’s found that daily creatine doses ranging from 4 to 10 grams did not significantly enhance their ability to perform daily activities.

Creatine’s Role in Neurological Diseases
Phosphocreatine reduction in the brain is a common factor in many neurological conditions. Creatine supplementation has been shown to increase phosphocreatine levels, potentially slowing disease progression. In animal studies involving Huntington’s disease, creatine restored phosphocreatine levels in the brain to 72% of pre-disease levels, compared to just 26% in control groups. This restoration was linked to improved daily function and a reduction in cell death.

Other studies in animals suggest that creatine could offer therapeutic benefits for conditions such as Alzheimer’s disease, epilepsy, and brain or spinal cord injuries. In cases of amyotrophic lateral sclerosis (ALS), creatine improved motor function, reduced muscle loss, and extended survival rates by 17%. While these findings are promising, human trials are necessary to confirm the efficacy of creatine as a supplementary treatment for these conditions. Researchers are optimistic about creatine's potential as an adjunct to conventional neurological treatments.

Enhancing Brain Function with Creatine
Creatine plays a vital role in brain health by supporting ATP production, which the brain requires in large amounts during complex tasks. Supplementation increases phosphocreatine stores, aiding ATP synthesis and boosting brain energy levels. Additionally, creatine may enhance brain function by elevating dopamine levels and improving mitochondrial efficiency.

Individuals following vegetarian or vegan diets often have lower creatine levels due to the absence of dietary sources like meat. Research indicates that vegetarians who supplemented with creatine experienced a 20% to 50% improvement in memory and intelligence test scores. For older adults, two weeks of creatine supplementation significantly enhanced memory and recall abilities. These findings suggest that creatine could protect against cognitive decline, support brain function, and mitigate age-related loss of muscle and strength.

Conclusion
While creatine is best known for its muscle-building properties, its emerging role in supporting cognitive health and combating neurological diseases is gaining recognition. Animal studies have provided compelling evidence, and preliminary human research suggests potential benefits for brain function, especially in vegetarians and older adults. As research progresses, creatine may become a cornerstone supplement for addressing cognitive decline and supporting overall brain health.

Reputable Suppliers & Discount Codes:

Use the discount code ‘MYNMN’ to get between 10% & 15% off from these reputable suppliers of Creatine:

ProHealth Longevity (15% off): https://shorturl.ac/7div9

DoNotAge (10% off): https://donotage.org/creatine

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